American Journal of Clinical Pathology · 2014 · 40 citations · 11 references
ComputingHealth InformaticsHematologyClinical Decision SupportClinical InformaticsTransfusion MedicineAlerting SystemsBlood Loss ManagementBlood Transfusion ManagementBlood Transfusion SafetyOrder EntryRed Blood Cell TransfusionAlert Generation SystemsAlert ManagementAlertsHemoglobin OptimizationPhysician Order EntryTransfusion Requirement MonitoringTransfusion Threshold Assessment
OBJECTIVES: To reduce unnecessary RBC transfusions, the computerized physician order entry (CPOE) system was programmed to require prescribers to select an indication for transfusion. An alert appeared if the patient's hemoglobin (Hb) level was above the threshold determined by the selected indication (adaptive alerts). METHODS: Data on RBC orders from the 4 months before the adaptive alerts were implemented were compared with the 10 months after implementation. RESULTS: Significantly fewer alerts were generated after the implementation, and the rate at which the alerts were heeded also increased. There was a trend toward fewer RBC units transfused after adaptive alert implementation. A large number of RBCs were ordered using a nonspecific transfusion indication, although many of these patients had antecedent Hb values close to the threshold. CONCLUSIONS: Electronically generated alerts can reduce but are insufficient to eliminate non-evidence-based transfusions. Analysis of the alerts suggests areas for CPOE improvement.
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Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery
Jeffrey L. Carson, Michael L. Terrin, Helaine Noveck et al. · New England Journal of Medicine · 2011 · 1.3K citations · Full text