Concepedia

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway

Satoshi Inoue, Gareth J. Browne, Gerry Melino, Gerald M. Cohen

Cell Death and Differentiation · 2009 · 245 citations · 37 references

DOI

Concepts

References

37

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

, , +17

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

, , +10

Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

Reiner U. Jänicke, Michael L. Sprengart, Mas Rina Wati et al. · Journal of Biological Chemistry · 1998 · 2K citations · Full text

, , +14

Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

Elizabeth A. Slee, Mary T. Harte, Ruth M. Kluck et al. · The Journal of Cell Biology · 1999 · 1.9K citations · Full text

, , +16

The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases

Natalie Roy · The EMBO Journal · 1997 · 1.3K citations · Full text

, , +14