Publication | Closed Access
Acidic Ionic Liquid–Catalyzed Highly Efficient Reaction of Indoles to α,β‐Unsaturated Ketones
14
Citations
35
References
2008
Year
Chemical EngineeringAcidic Ionic LiquidEngineeringCatalytic SynthesisOrganic ChemistryCatalysisMolecular CatalysisChemistryNew ProtocolMichael ReactionSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringNatural Product Synthesis
Abstract A novel method for the Michael reaction of indoles to α,β‐unsaturated ketones catalyzed by acidic ionic liquid is reported. We obtained the corresponding products in excellent yields in the presence of [hmim]HSO4. Development of this method has resulted in a new protocol for the synthesis of β‐indolylketones.
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