Role of spinal metabotropic glutamate receptor subtype 5 in the development of tolerance to morphine-induced antinociception in rat

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

Keith A. Trujillo, Huda Akil · Science · 1991 · 1.2K citations

Medicine, Neuroscience, Pharmacology +17

Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

Li Chen, Li-Yen Mae Huang · Nature · 1992 · 965 citations

Medicine, Neurobiology, Neuroscience +14

Unveiling the Functions of Presynaptic Metabotropic Glutamate Receptors in the Central Nervous System

D D Schoepp · Journal of Pharmacology and Experimental Therapeutics · 2001 · 690 citations

Life Sciences, Neurobiology, Neuroscience +17

Activation of Metabotropic Glutamate Receptor 5 Has Direct Excitatory Effects and Potentiates NMDA Receptor Currents in Neurons of the Subthalamic Nucleus

Hazar Awad, George W. Hubert, Yoland Smith et al. · Journal of Neuroscience · 2000 · 420 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Lumbar catheterization of the spinal subarachnoid space in the rat

Rolf Størkson, Anne Kjørsvik, Arne Tjølsen et al. · Journal of Neuroscience Methods · 1996 · 365 citations

Medicine, Neurological Surgery, Neurosurgery +14