EARLY EFFECTS OF EPINEPHRINE AND PILOCARPINE ON THE INTRAOCULAR PRESSURE AND THE EPISCLERAL VENOUS PRESSURE IN THE NORMAL HUMAN EYE

Abstract

Topical instillation of one drop of epinephrine 1% and pilocarpine 2% in normal human eyes were found to give a transient increase of the intraocular pressure (IOP) and the episcleral venous pressure (P rv ) of about 2 to 5.5 mmHg. The maxima were reached in 5 to 10 minutes after instillation. During the rising phase the change of the P rv preceded that of the IOP.