Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens

A psychomotor stimulant theory of addiction.

Roy A. Wise, Michael A. Bozarth · Psychological Review · 1987 · 2.7K citations

Medicine, Neuroscience, Pharmacology +17

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

Keith A. Trujillo, Huda Akil · Science · 1991 · 1.2K citations

Medicine, Neuroscience, Pharmacology +17

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

Francesco E. Pontieri, Gianluigi Tanda, G. Di Chiara · Proceedings of the National Academy of Sciences · 1995 · 868 citations

Medicine, Neuroscience, Pharmacology +17

Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats.

R. Bals-Kubik, A. Ableitner, A. Herz et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 528 citations

Medicine, Neuroscience, Pharmacology +17

Drug reinforcement studied by the use of place conditioning in rat

Ronald F. Mucha, Derek van der Kooy, Martha O'Shaughnessy et al. · Brain Research · 1982 · 489 citations

Public Health, Behavioral Sciences, Behavioral Neuroscience +11