Concepedia

Novel polyamine derivatives as potent competitive inhibitors of Trypanosoma cruzi trypanothione reductase

Mary C. O’Sullivan, Qibing Zhou

Bioorganic & Medicinal Chemistry Letters · 1995 · 26 citations · 15 references

DOI

Concepts

References

15

Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in Trypanosomatids

Alan H. Fairlamb, Peter Blackburn, Peter Ulrich et al. · Science · 1985 · 678 citations

, , +15

Purification and characterization of trypanothione reductase from Crithidia fasciculata, a new member of the family of disulfide-containing flavoprotein reductases

Spencer L. Shames, Alan H. Fairlamb, Anthony Cerami et al. · Biochemistry · 1986 · 271 citations

, , +7

Disulfide‐Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

R. Heiner Schirmer, Joachim G. Müller, R. Luise Krauth‐Siegel · Angewandte Chemie International Edition in English · 1995 · 214 citations

, , +17

Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures

Timothy J. Benson, James H. McKie, J. Garforth et al. · Biochemical Journal · 1992 · 154 citations · Full text

, , +15

Trypanothione reductase from <i>Trypanosoma cruzi</i>

Maria C. JOCKERS‐SCHERÜBL, R. Heiner Schirmer, R. Luise Krauth‐Siegel · European Journal of Biochemistry · 1989 · 150 citations · Full text

, , +15