PubMed · 1991 · 46 citations · 0 references
MedicineInternal MedicinePharmacologyAllergyClinical PharmacologyHypersensitivityDrug AllergyNasal PhysiologyNasal PolyposisNasal PolypsAspirin ResponseControl Group DesignMatched Control GroupNasal Allergy AssessmentNasal HyperreactivityNasal InflammationNasal Symptoms
The authors have studied nasal provocation testing (NPT) with aspirin in 45 aspirin-sensitive patients (40 affected by nasal polyposis) and in 38 aspirin-tolerant patients (27 affected by nasal polyposis). The test was positive in 37.7% of aspirin-intolerant subjects, but only in 7.9% of subjects in the control group (P less than .01).