Paraproteinaemia in neurological disease: incidence, associations, and classification of monoclonal immunoglobulins.

Abstract

Fifty-six patients presenting with neurological complaints were found to have paraproteinaemia unassociated with immunocytic malignancy; 16 patients presented with peripheral neuropathy. There was an association between IgM paraproteinaemia and an idiopathic neuropathy with markedly slowed nerve conduction velocities.