Progression of Nephropathy in Type 2 Diabetes: The Glycation Gap Is a Significant Predictor after Adjustment for Glycohemoglobin (Hb A1c)

Abstract

GG predicts the progression of nephropathy in type 2 diabetic patients independently of fructosamine and even after adjustment for Hb A(1c). The joint use of the glycation gap and fructosamine as measures of nonglycemic and glycemic determinants of glycation, respectively, may improve evaluation of the risk of nephropathy and of the glycemic control desirable for the individual patient.