The Nephron journals/Nephron journals · 2008 · 21 citations · 0 references
MedicineHematologyNephrologyKidney TransplantationRenal PathologyRenal PathophysiologyAcute RejectionAllograft RejectionAnemiaImmunosuppression In Kidney TransplantationTransplant PharmacologyTransplant RejectionAcute Renal Allograft RejectionChronic Renal InsufficiencyHemolytic CrisisMicroangiopathic Hemolytic AnemiaTransplantation
The present study describes 3 adult patients with hemolytic uremic syndrome (HUS) leading to chronic renal failure. Following renal transplantation, the 3 patients developed microangiopathic hemolytic anemia associated with acute rejection crises and graft failure. In 2 patients the renal histology of the transplanted kidney was consistent with HUS. It is concluded that, in adult patients, HUS may recur after renal transplantation and contribute to renal graft failure.