Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification

Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

Lovisa Hessle, H. Clarke Anderson, Sonoko Narisawa et al. · Proceedings of the National Academy of Sciences · 2002 · 859 citations · Full text

Medicine, Biochemistry, Molecular Biology +17

Role of the Mouse <i>ank</i> Gene in Control of Tissue Calcification and Arthritis

Andrew M. Ho, Michelle D. Johnson, David M. Kingsley · Science · 2000 · 647 citations

Medicine, Genetics, Molecular Biology +14

Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification

Frank Rutsch, Nico Ruf, Sucheta M. Vaingankar et al. · Nature Genetics · 2003 · 603 citations

Life Sciences, Genetics, Molecular Genetics +8

Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

Monzur Murshed, Dympna Harmey, José Luís Millán et al. · Genes & Development · 2005 · 602 citations · Full text

Medicine, Molecular Biology, Physiology +17

Phosphate is a specific signal for induction of osteopontin gene expression

George R. Beck, Brad Zerler, Elizabeth Morán · Proceedings of the National Academy of Sciences · 2000 · 525 citations

Medicine, Developmental Biology, Bone Metabolism +16