Neurology · 1997 · 40 citations · 2 references
MedicineNeurologyNeuroscienceDiagnostic ImagingEpilepsyMemoryBrain ImagingHippocampal SystemsMagnetic Resonance ImagingMemory AssessmentNeuroimaging In EpilepsyNeuropsychological AssessmentHippocampal InvolvementHippocampal VolumetryMagnetic Resonance Relaxation TimesMemory DysfunctionNeuropsychological ImpairmentRelaxation TimesT2 RelaxationVerbal Memory
The structural damage in the left hippocampus measured by volumetric MRI was shown to correlate with the impairment of verbal memory performance in chronic left-sided temporal lobe epilepsy. [1] In addition to volumetric measurements, MRI T2 relaxometry was suggested to provide a sensitive quantitative means of assessing the degree of hippocampal pathology in temporal lobe epilepsy. [2] We showed earlier in separate patient populations that patients with partial epilepsy of unknown etiology exhibit subtle verbal memory dysfunction measured by neuropsychological tests [3] and mild hippocampal damage measured by MRI volumetry [4] already at the time of diagnosis. There are no data of the correlation of MRI-based quantitative measurements of hippocampus with the memory performance in newly diagnosed patients. We measured hippocampal volumes and T2 relaxation times using a 1.5-T MRI imager in …
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