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Thermostabilization of a chimeric enzyme by residue substitutions: four amino acid residues in loop regions are responsible for the thermostability of Thermus thermophilus isopropylmalate dehydrogenase

Chimeric EnzymeBiochemistryBioenergeticsProtein FoldingNatural SciencesEnzyme CatalysisMolecular BiologyEnzyme SpecificityStructure-function Enzyme KineticsLoop RegionsMedicineEnzymatic ModificationResidue Substitutions