Concepedia

Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells

Hua Jiang, Chun-Hui Hou, Shu-Bing Zhang, Heng-Yue Xie, Wei-Ying Zhou, Qi-Huang Jin, Xiao-Dong Cheng, R Qian, Xuejun Zhang

European Journal of Pharmacology · 2007 · 91 citations · 30 references

DOI

Concepts

References

30

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

, , +12

ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

Yanping Zhang, Yue Xiong, Wendell G. Yarbrough · Cell · 1998 · 1.6K citations · Full text

, , +16

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

Philip W. Hinds, Sibylle Mittnacht, Vjekoslav Dulić et al. · Cell · 1992 · 1K citations

, , +12

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Keith D. Robertson, Slimane Ait‐Si‐Ali, Tomoki Yokochi et al. · Nature Genetics · 2000 · 942 citations

, , +12

Three-Dimensional Structure of the Apoptosome

Devrim Acehan, Xuejun Jiang, David Morgan et al. · Molecular Cell · 2002 · 895 citations · Full text

, , +12