Highly Stereoselective Synthesis of β‐Lactams Utilizing α‐Chloroimines as New and Powerful Chiral Inductors

Abstract

A new and efficient one-pot approach towards chiral azetidin-2-ones has been developed starting from (2S)-chloro-1-propanol, affording novel β-lactams in high diastereomeric (80–89 %) and enantiomeric excess (90 %). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2111/2008/z800845_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.