Synthesis · 2008 · 29 citations · 0 references
PharmacyChemistryMedicinal ChemistrySynthetic Medicinal ChemistryPlant Natural Product BiosynthesisAldol ReactionNatural Product SynthesisOlefin MetathesisOlefin Metathesis CatalysisStereoselective Synthesis
A stereoselective total synthesis of the phytotoxic compound herbarumin III has been achieved by utilizing Crimmins’s aldol approach, 1,3-syn asymmetric reduction, and an olefin metathesis reaction as the key steps.