The Unexpected Diaxial Orientation of <i>cis-</i>3,5-Difluoropiperidine in Water: A Potent CF- - -NH Charge-Dipole Effect

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTThe Unexpected Diaxial Orientation of cis-3,5-Difluoropiperidine in Water: A Potent CF- - -NH Charge-Dipole EffectJames P. Snyder, Nizal S. Chandrakumar, Hirofumi Sato, and David C. LankinView Author Information Department of Chemistry, Emory University Atlanta, Georgia 30322 Searle Research and Development 4901 Searle Parkway, Skokie, Illinois 60077 Department of Chemistry Department of Theoretical Study, Institute for Molecular Science, Okazaki National Research Institutes Okazaki 444-8585, Japan Cite this: J. Am. Chem. Soc. 2000, 122, 3, 544–545Publication Date (Web):January 8, 2000Publication History Received23 September 1999Revised8 December 1999Published online8 January 2000Published inissue 1 January 2000https://pubs.acs.org/doi/10.1021/ja9934504https://doi.org/10.1021/ja9934504rapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views1215Altmetric-Citations75LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Fluorine,Molecular structure,Noncovalent interactions,Piperidines,Salts Get e-Alerts