Advanced Materials · 2006 · 238 citations · 35 references
PharmacyBioengineeringPharmaceuticsDrug DeliveryStimuli-responsive Drug DeliveryUltrasoundControlled Release MechanismsDrug Delivery BiomaterialsDrug Delivery SystemsDrug EncapsulationImplantable Drug Delivery SystemsPolymeric Drug Delivery SystemsDrug Delivery PolymersDrug Reservoir SystemsImplantable Drug Delivery DevicesIn Vivo DeliveryMesoporous MaterialsPulsatile Drug ReleaseUltrasound-responsive ReleaseUltrasound-triggered Release
Ultrasound is used as an external trigger for the pulsatile release of the drug ibuprofen. The system is composed of mesoporous silica as the drug reservoir and poly(dimethylsiloxane) (PDMS) as an implantable body. This system could find use for in vivo delivery of drugs in response to changes in physiological conditions.
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A New Property of MCM-41: Drug Delivery System
María Vallet‐Regí, A. Rámila, R. P. del Real et al. · Chemistry of Materials · 2000 · 2.2K citations
Cheng‐Yu Lai, Brian G. Trewyn, Dušan M. Jeftinija et al. · Journal of the American Chemical Society · 2003 · 1.7K citations
E.B. Flint, Kenneth S. Suslick · Science · 1991 · 1.2K citations
Natural Sciences, Chemistry, Physics +16