Ultrasound‐Triggered Smart Drug Release from a Poly(dimethylsiloxane)– Mesoporous Silica Composite

Han‐Joon Kim, Hirofumi Matsuda, Henghui Zhou, Itaru Honma

Advanced Materials · 2006 · 238 citations · 35 references

Concepts

Abstract

Ultrasound is used as an external trigger for the pulsatile release of the drug ibuprofen. The system is composed of mesoporous silica as the drug reservoir and poly(dimethylsiloxane) (PDMS) as an implantable body. This system could find use for in vivo delivery of drugs in response to changes in physiological conditions.

References

35