Significance of p53 overexpression in urinary bladder transitional cell carcinoma in situ before and after bacillus Calmette-Guérin treatment

Mutations in the p53 gene occur in diverse human tumour types

Janice Nigro, Suzanne J. Baker, Antonette C. Preisinger et al. · Nature · 1989 · 2.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

Wafik S. El‐Deiry, Harper JW, O'Connor Pm et al. · PubMed · 1994 · 2K citations

Life Sciences, Cell Biology, Molecular Biology +17

The p53 proto-oncogene can act as a suppressor of transformation

Cathy A. Finlay, Philip W. Hinds, Arnold J. Levine · Cell · 1989 · 2K citations

Medicine, Molecular Biology, Oncology +12

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner, Jennifer A. Pietenpol, Sam Thiagalingam et al. · Nature · 1993 · 1.5K citations

Medicine, Cancer Biology, Oncology +16

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

Cathy A. Finlay, Philip W. Hinds, Tse‐Hua Tan et al. · Molecular and Cellular Biology · 1988 · 1.1K citations · Full text

Medicine, Genetics, Molecular Biology +14