Adaptation of Chinese hamster ovary cells to low culture temperature: Cell growth and recombinant protein production

A Glycine-rich RNA-binding Protein Mediating Cold-inducible Suppression of Mammalian Cell Growth

Hiroyuki Nishiyama, Katsuhiko Itoh, Yoshiyuki Kaneko et al. · The Journal of Cell Biology · 1997 · 386 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Effect of low culture temperature on specific productivity, transcription level, and heterogeneity of erythropoietin in Chinese hamster ovary cells

Sung Kwan Yoon, Ji Yong Song, Gyun Min Lee · Biotechnology and Bioengineering · 2003 · 244 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure

Sang Jick Kim, No Soo Kim, Chun Jeih Ryu et al. · Biotechnology and Bioengineering · 1998 · 221 citations

Pharmacy, Biotechnology, Molecular Biology +17

Evidence that monoclonal antibody production kinetics is related to the integral of the viable cells curve in batch systems

James Renard, Roberto Spagnoli, C. Mazier et al. · Biotechnology Letters · 1988 · 190 citations

Pharmacy, Immunology, Monoclonal Antibodies +7

Maximizing interferon‐γ production by chinese hamster ovary cells through temperature shift optimization: <i>Experimental and modeling</i>

Stephen R. Fox, Upasana A. Patel, Miranda G.S. Yap et al. · Biotechnology and Bioengineering · 2003 · 173 citations

Life Sciences, Biotechnology, Cell Biology +17