Thermodynamic Behavior of a Supramolecular System Self-Assembled by Electrostatic Interaction in Aqueous Solution. Results And Theoretical Analysis

Abstract

The acid−base and association properties of oppositely charged cyclodextrins in aqueous solution have been investigated by potentiometry. The experimental thermodynamic constants can be analyzed with a theoretical approach leading to structural data in satisfactory agreement with the crystallographic structures of the parent compounds and previous NMR investigations. The corresponding theory is expected to be helpful for understanding and for predicting the behavior of many supramolecular systems involving charged organic molecules.