Bax, Bcl-2, and p53 Expression in Endometrial Cancer

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

Toshiyuki Miyashita, Stanisław Krajewski, Maryla Krajewska et al. · PubMed · 1994 · 2.2K citations

Life Sciences, Cell Biology, Oncology +13

Somatic Frameshift Mutations in the <i>BAX</i> Gene in Colon Cancers of the Microsatellite Mutator Phenotype

Nicholas J. Rampino, Hiroyuki Yamamoto, Yurij Ionov et al. · Science · 1997 · 1.3K citations

Life Sciences, Genetics, Oncology +17

Genetic instability of microsatellites in endometrial carcinoma.

John I. Risinger, Andrew Berchuck, Matthew F. Kohler et al. · PubMed · 1993 · 521 citations

Medicine, Genetics, Oncology +17

A simple p53 functional assay for screening cell lines, blood, and tumors.

Jean‐Michel Flaman, Thierry Frébourg, Viviane Moreau et al. · Proceedings of the National Academy of Sciences · 1995 · 451 citations

Life Sciences, Molecular Biology, Molecular Genetics +13

p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

Hironori Tashiro, Christina Isacson, Ross L. Levine et al. · PubMed · 1997 · 348 citations

Medicine, Molecular Genetics, Oncology +12