SPECIFIC METABOLIC REPRESSION OF THREE INDUCED ENZYMES IN <i>ESCHERICHIA COLI</i>

Abstract

It is well known that the synthesis of many induced catabolic enzymes in micro-organisms is repressed by glucose. Earlier studies on ,B-galacto- sidase formation in Eacherichia coli have estab- lished the following facts (see Mandelstam, 1961, 1962). The glucose effect is not specific, and any compound that the cells can use as a source of carbon and energy can repress the formation of fl-galactosidase, although it may not do so in usual