Treatment of Coccidioidomycosis Infection of Bone with Local Amphotericin B Suction-Irrigation

Stephen R. Stein, Claude A. Leukens, Raymond J. Bagg

Clinical Orthopaedics and Related Research · 1975 · 12 citations · 0 references

Concepts

Abstract

A 29-year-old man with coccidioidomycosis of the tarsal bones and toxic reactions to intravenous Amphotericin B was treated by surgical curettage and local suction-irrigation system of Amphotericin B. The patient responded to treatment and was free of disease 2 years later. Local suction-irrigation with Amphotericin B may be a valuable adjunct in the treatment of coccidioidomycosis infection of bone.