Concise Approach to Benzisothiazol-3(2<i>H</i>)-one via Copper-Catalyzed Tandem Reaction of <i>o</i>-Bromobenzamide and Potassium Thiocyanate in Water

Abstract

A concise approach to various benzisothiazol-3(2H)-one derivatives has been developed by copper-catalyzed the reaction of o-bromobenzamide derivatives with potassium thiocyanate (KSCN) in water. The reaction proceeds via a tandem reaction with S-C bond and S-N bond formation.