JAMA · 1967 · 46 citations · 0 references
MedicineOncologySurgeryBreast OncologyOncologic SurgerySurgical OncologyBreast Cancer RadiotherapyBreast Cancer SurgeryBreast SurgeryRadiation TherapyComparative Clinical TrialsRadiation Therapy CombinationsSurvival RatesWedge ResectionWell-beingWide Excision
Concern for the patients' morale as well as their physical well-being has prompted me to present a preliminary report on our experience in local excision and radiation therapy for early breast cancer at the Ontario Institute, Toronto. Many authors such as Porritt,<sup>1</sup>Smithers,<sup>2</sup>Mustakallio,<sup>3</sup>and de Winter<sup>4</sup>have emphasized a similar concern, and all have been impressed by the excellent survival rates following wide excision and irradiation for early carcinoma of the breast. Actually, if the five-year survival rate is employed as the parameter, no superior method of treatment has so far been demonstrated in stages I and II breast cancer. This conclusion has been amply supported by the prospective clinical trials comparing methods of treatment which have been reported by Kaae and Johansen<sup>5</sup>as well as Paterson and Russell.<sup>6</sup>Also, biometricians such as Park and Lees,<sup>7</sup>McKinnon,<sup>8</sup>and Shimkin<sup>9</sup>have