Opioid receptor-mediated inhibition of dopamine and acetylcholine release from slices of rat nucleus accumbens, olfactory tubercle and frontal cortex

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

G. Di Chiara, Assunta Impérato · Journal of Pharmacology and Experimental Therapeutics · 1988 · 922 citations

Medicine, Neuroscience, Pharmacology +17

Opposing roles for D-1 and D-2 dopamine receptors in efflux of cyclic AMP from rat neostriatum

J.C. Stoof, John W. Kebabian · Nature · 1981 · 917 citations

Life Sciences, Neurobiology, Neuroscience +16

U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.

Philip F. VonVoigtlander, Robert A. Lahti, James H. Ludens · Journal of Pharmacology and Experimental Therapeutics · 1983 · 816 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

Henry I. Mosberg, R. P. Hurst, Victor J. Hruby et al. · Proceedings of the National Academy of Sciences · 1983 · 739 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Binaltorphimine and nor-binaltorphimine, potent and selective k-opioid receptor antagonists

Philip S. Portoghese, A. W. Lipkowski, A.E. Takemori · Life Sciences · 1987 · 533 citations

Medicine, Medicinal Chemistry, Pharmacology +10