Convertible Organic Nanoparticles for Near‐Infrared Photothermal Ablation of Cancer Cells

Jaemoon Yang, Jihye Choi, Doyeon Bang, Eunjung Kim, Eun‐Kyung Lim, Huiyul Park, Jin‐Suck Suh, Kwangyeol Lee, Kyung‐Hwa Yoo, Eun‐Kyung Kim,

Angewandte Chemie International Edition · 2010 · 514 citations · 19 references

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Abstract

Infiltrate and destroy: In an environment rich in protonating or oxidative species, such as the intracellular milieu of cancer cells, the main absorption band of spherical, water-soluble polyaniline nanoparticles was red-shifted to a near-infrared (NIR) wavelength as a result of the formation of the emeraldine salt (see picture). The doped nanoparticles caused photothermal ablation of cancer cells upon NIR laser irradiation in vitro and in vivo. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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