The Journal of Antibiotics · 1969 · 28 citations · 9 references
PharmacyMedicinal ChemistryMicrobiologyMycologyNatural Product BiosynthesisMicrobial Natural Product BiosynthesisAntibiotic DiscoveryMacrolide Antibiotics
The biosynthesis of lucensomycin in cultures of Streptomyces lucensis has been studied using 14C-labelled precursors. The aglycone arises from two propionate and twelve acetate units. One propionate unit provides the chain-initiating unit, whilst the second, involved in chain-extension, undergoes oxidation of its methyl group to form the free carboxyl function of the aglycone.
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Degradation of labeled propionic and acetic acids
E.F. Phares · Archives of Biochemistry and Biophysics · 1951 · 398 citations
The structure of the macrolide antibiotic pimaricin
B. T. GOLDING, Randal W. Richards, W.E. Meyer et al. · Tetrahedron Letters · 1966 · 54 citations
Nystatin. IV. The Stereochemistry of Mycosamine
Malcolm von Saltza, James D. Dutcher, J. G. REID et al. · The Journal of Organic Chemistry · 1963 · 43 citations
Nystatin. Part V. Biosynthetic definition of some structural features
A. J. Birch, Cedric W. Holzapfel, R. W. RICKARDS et al. · Tetrahedron Letters · 1964 · 34 citations
The structure of lucensomycin. Part II
S. Gaudiano, P. BRAVO, A. Quilico · Tetrahedron Letters · 1966 · 28 citations