De novo quantitative bisulfite sequencing using the pyrosequencing technology

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Marianne Frommer, Louise E. McDonald, David Millar et al. · Proceedings of the National Academy of Sciences · 1992 · 3.3K citations

Life Sciences, Genetics, Molecular Biology +14

A Sequencing Method Based on Real-Time Pyrophosphate

Mostafa Ronaghi, Mathias Uhlén, Pål Nyrén · Science · 1998 · 1.6K citations

Life Sciences, Biotechnology, Molecular Biology +7

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

Amy T. Hark, Christopher J. Schoenherr, David J. Katz et al. · Nature · 2000 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +14

Real-Time DNA Sequencing Using Detection of Pyrophosphate Release

Mostafa Ronaghi, Samer Karamohamed, Bertil Pettersson et al. · Analytical Biochemistry · 1996 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +11

Sensitive and quantitative universal Pyrosequencing™ methylation analysis of CpG sites

Stefano Colella, Lanlan Shen, Keith Baggerly et al. · BioTechniques · 2003 · 498 citations · Full text

Life Sciences, Genetics, Molecular Biology +12