Effect of ProRoot^® MTA mixed with chlorhexidine on apoptosis and cell cycle of fibroblasts and macrophages <i>in vitro</i>*

Abstract

This in vitro study demonstrated that the substitution of CHX for sterile water in MTA increases its cytotoxicity. This suggests that the potentially beneficial antimicrobial effect of CHX may be accompanied by an increase in the cytotoxicity of the resulting MTA-based material.