American Journal of Psychiatry · 1956 · 51 citations · 0 references
MedicinePharmacologyPharmacotherapyClinical PharmacologyPharmacodynamicsPsychopharmacologyAdverse Drug ReactionsAdverse EffectsAnaphylaxisDrug AllergyMedication Side Effect ManagementSide EffectsDrug-related Side EffectsIndirect EffectsPsychiatric Complications
1. Chlorpromazine has many undesirable effects, most of which are transient and of relatively minor clinical significance. 2. Complications of greater severity occur in a significant number of cases but generally resolve rapidly and without residuals. 3. Four categories of complications are distinguishable: direct or indirect action on various levels of the nervous System, allergic-type reactions, responses of indefinite origin, and indirect effects of drug action. 4. Despite its numerous undesirable effects chlorpromazine is clinically a relatively safe drug.