Synthesis of Cucurbituril-spermine-[2]rotaxanes of the Amide-type

Abstract

Abstract [2]Rotaxanes with the macrocyclic ligand cucurbituril were prepared in yields between 10 and 90% from the reaction of the spermine complex with cucurbituril and different carboxylic acid chlorides in a two phase Schotten-Baumann reaction. This reaction type offers the possibility to synthesize a lot of different [2]rotaxanes. They are characterised by elemental analysis, 1H-NMR spectroscopy and mass spectrometry.