Advanced Materials · 2001 · 204 citations · 1 references
Life SciencesBiotechnologyNeuroscienceMolecular RecognitionNanobiotechnologyNanotechnologyAntibody-antigen RecognitionCell-nanoparticle InteractionsFluorescence MicroscopyNanomedicineQuantum DotsSemiconductor NanomaterialsNanometer-scale ImagingNeuroblastoma BiologyPeptide Antigen RecognitionPeptide Recognition ElementsQuantum Dot FluorescenceQuantum Dot ImagingSemiconductor Quantum DotsTargeted Bioimaging
Attachment of semiconductor quantum dots to living neurons utilizing antibody and peptide recognition molecules has been achieved. It is shown that peptide recognition molecules provide nanometer-scale control over the targeting and separation distance between the quantum dot and the cell. The Figure shows a fluorescence image of CdS quantum dots attached by antibody binding to human neuroblastoma cells.
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