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The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity
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1986
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New AlkaloidsSpectroscopic DataBioorganic ChemistryStructures 1BiochemistryActive IngredientNatural SciencesMedicineMarked Anticholinesterase ActivityPhytochemistryPhytopharmacologyNew Lycopodium AlkaloidsChemical BiologyPharmacologyInhibitory ActivityHuperzine ADrug DiscoveryNatural Product Synthesis
Huperzine A and B, two new Lycopodium alkaloids isolated from Huperziaserrata (Thunb.) Trev., are shown to possess structures 1 and 3, respectively, on the basis of chemical and spectroscopic data.