The False Negative Rate in Cervical Cytology

Abstract

Cervical samples that are preserved in a liquid suspension and prepared using the density gradient monolayer technology have many advantages over conventional cervical cytologic smear preparations. The quality of cell preservation and presentation is superior. Elimination of obscuring material, homogeneity of the sample and standardized quality work together to produce preparations that can be effectively and reliably screened by cytotechnologists. These preparations should greatly enhance the reliability of machine-based screening in the future.