Concepedia
Bioorganic & Medicinal Chemistry · 2013 · 28 citations · 23 references
Open access
Medicinal ChemistryBiochemistryMedicineNatural SciencesPharmacological AgentAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug DiscoveryNovel Hdac Inhibitors
23
A synthetic inhibitor of histone deacetylase, MS-27-275, with marked <i>in vivo</i> antitumor activity against human tumors
Akiko Saito, Takashi Yamashita, Yukiyasu Mariko et al. · Proceedings of the National Academy of Sciences · 1999 · 696 citations · Full text
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo.
Lisa M. Butler, David B. Agus, Howard I. Scher et al. · PubMed · 2000 · 617 citations
Chemoprevention Strategy, Prostate Cancer Cells, Cancer Biology +18
JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity
Janine Arts, Peter King, Ann Marin et al. · Clinical Cancer Research · 2009 · 230 citations
Hybrid polar histone deacetylase inhibitor induces apoptosis and CD95/CD95 ligand expression in human neuroblastoma.
Richard D. Glick, Steven Swendeman, Dennis C. Coffey et al. · PubMed · 1999 · 186 citations
Human Neuroblastoma, Chemoprevention Strategy, Apoptosis +16
Biophysical Fragment Screening of the β <sub>1</sub> -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design
J.A. Christopher, Jason Brown, A.S. Dore et al. · Journal of Medicinal Chemistry · 2013 · 157 citations · Full text