Intranasal vaccination with poly(lactide‐<i>co</i>‐glycolide) microparticles containing a peptide T of Ole e 1 prevents mice against sensitization

Abstract

These results demonstrate that i.n. immunization with peptide T-PLGA microparticles is effective in preventing subsequent allergic sensitization to Ole e 1. Our data indicate that peptide-PLGA microparticles may be promising candidates for the design of nasal vaccines against allergic diseases in humans.