Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

Douglas A. Melton, Paul A. Krieg, Michael R. Rebagliati et al. · Nucleic Acids Research · 1984 · 6.4K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +11

Selective extraction of polyoma DNA from infected mouse cell cultures

Bernhard Hirt · Journal of Molecular Biology · 1967 · 5.3K citations

Life Sciences, Cell Biology, Molecular Biology +11

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

Michael N. Berry, Daniel S. Friend · The Journal of Cell Biology · 1969 · 4.4K citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels

Michael McDonell, Martha N. Simon, F. William Studier · Journal of Molecular Biology · 1977 · 1.6K citations

Life Sciences, Genetics, Molecular Biology +10