Peroxisome Proliferator-Activated Receptor α and γ Ligands Differentially Affect Smooth Muscle Cell Proliferation and Migration

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

Inflammation, Cytokine, Anti-inflammatory +8

Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators

Susanna S.T. Lee, Thierry Pineau, John Drago et al. · Molecular and Cellular Biology · 1995 · 1.6K citations · Full text

Lipid Peroxidation, Oxidative Stress, Metabolic Signaling +16

Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

Bart Staels, Wolfgang Köenig, Régine Merval et al. · Nature · 1998 · 1.1K citations

Molecular Pharmacology, Muscle Physiology, Molecular Physiology +14

Peroxisome Proliferator-activated Receptors α and γ Are Activated by Indomethacin and Other Non-steroidal Anti-inflammatory Drugs

Jürgen M. Lehmann, James M. Lenhard, Beverly B. Oliver et al. · Journal of Biological Chemistry · 1997 · 1.1K citations · Full text

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

William R. Oliver, Jennifer L. Shenk, Mike R. Snaith et al. · Proceedings of the National Academy of Sciences · 2001 · 1K citations · Full text

Molecular Pharmacology, Metabolic Syndrome, Insulin Signaling +15