Tumor-Specific T Cells in Human Merkel Cell Carcinomas: A Possible Role for Tregs and T-Cell Exhaustion in Reducing T-Cell Responses

Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma

Huichen Feng, Masahiro Shuda, Yuan Chang et al. · Science · 2008 · 3.2K citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Julie R. Brahmer, Charles G. Drake, Ira Wollner et al. · Journal of Clinical Oncology · 2010 · 2.9K citations · Full text

Medicine, Oncology, Pharmacology +17

Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

Steven A. Rosenberg, James Chih‐Hsin Yang, Richard M. Sherry et al. · Clinical Cancer Research · 2011 · 2.1K citations · Full text

Life Sciences, Immunology, Oncology +12

Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

Mojgan Ahmadzadeh, Laura A. Johnson, Bianca Heemskerk et al. · Blood · 2009 · 1.8K citations · Full text

Medicine, Immunology, Oncology +12

Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features

Michelle Heath, Natalia Jaimes, Bianca D. Lemos et al. · Journal of the American Academy of Dermatology · 2008 · 919 citations · Full text

Veterinary Medicine, Oncology, Pathology +11