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How important is protein kinase C in μ-opioid receptor desensitization and morphine tolerance?

Opioid EpidemicMolecular PharmacologyMorphine ToleranceMolecular PhysiologySignal TransductionProtein Kinase CMedicinePhysiologyμ-Opioid Receptor DesensitizationReceptor (Biochemistry)NeuropharmacologyPharmacotherapyPharmacologyCell SignalingOpioid Use DisorderHealth Sciences