Comparative metabolism and DNA binding of 1-, 2-, and 4-nitropyrene in rats

Formation of DNA adducts in vitro and in Salmonella typhimurium upon metabolic reduction of the environmental mutagen 1-nitropyrene.

Paul C. Howard, Robert H. Heflich, Frederick E. Evans et al. · PubMed · 1983 · 168 citations

Pharmacy, Biochemistry, Toxicology +17

Tumorigenicity of nitrated derivatives of pyrene, benz[a]anthracene, chrysene and benzo[a]pyrene in the newborn mouse assay

Peter G. Wislocki, Edward S. Bagan, Anthony Y.H. Lu et al. · Carcinogenesis · 1986 · 153 citations

Pharmacy, Toxicology, Carcinogenesis +14

Induction of rat mammary gland tumors by 1-nitropyrene, a recently recognized environmental mutagen.

Masao Hirose, Mei‐Sie Lee, Ching Y. Wang et al. · PubMed · 1984 · 149 citations

Veterinary Medicine, Toxicology, Carcinogenesis +16

The genotoxicity, metabolism and carcinogenicity of nitrated polycyclic aromatic hydrocarbons

Herbert S. Rosenkranz, Robert Mermelstein · Journal of Environmental Science and Health Part C Environmental Carcinogenesis Reviews · 1985 · 112 citations

Pharmacy, Environmental Sciences, Toxicology +17

Tumorigenicity and metabolism of 1-nitropyrene in A/J mice

Karam El‐Bayoumy, Stephen S. Hecht, Terri Sackl et al. · Carcinogenesis · 1984 · 79 citations

Medicine, Oncology, Pharmacology +6