Lactated Ringer???s Solution and Hetastarch but Not Plasma Resuscitation after Rat Hemorrhagic Shock Is Associated with Immediate Lung Apoptosis by the Up-regulation of the Bax Protein

Abstract

Apoptosis after volume resuscitation of hemorrhagic shock can be affected by the type of resuscitation fluid used. Manufactured fluids such as lactated Ringer's solution and 6% hetastarch resuscitation resulted in the highest degree of lung apoptosis. The plasma component of whole blood resulted in the least apoptosis. The process of apoptosis after hemorrhagic shock resuscitation involves the Bax protein.