Identification of a potent and selective oxytocin antagonist, from screening a fully encoded differential release combinatorial chemical library

General method for rapid synthesis of multicomponent peptide mixtures

Árpád Furka, Ferenc Sebestyén, MAMO ASGEDOM et al. · International journal of peptide & protein research · 1991 · 1.2K citations

Pharmacy, Biochemistry, Chemistry +10

RECAPRetrosynthetic Combinatorial Analysis Procedure:  A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial Chemistry

Xiao Qing Lewell, Duncan B. Judd, Michael M. Hann · Journal of Chemical Information and Computer Sciences · 1998 · 701 citations

Pharmacy, Medicinal Chemistry, Combinatorial Chemistry +13

Discovery of biologically active peptides in random libraries: solution-phase testing after staged orthogonal release from resin beads.

S. E. Salmon, Kit S. Lam, Michal Lebl et al. · Proceedings of the National Academy of Sciences · 1993 · 100 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +17

Structural studies of reagents for peptide bond formation: Crystal and molecular structures of HBTU and HATU

Iman Abdelmoty, Fernando Alberício, Louis A. Carpino et al. · Letters in Peptide Science · 1994 · 99 citations

Natural Sciences, Biochemistry, Chemistry +16

Deconvolution of Combinatorial Libraries for Drug Discovery: A Model System

Susan M. Freier, Danielle Konings, Jacqueline R. Wyatt et al. · Journal of Medicinal Chemistry · 1995 · 77 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5