Concepedia

Inhibition of allergen-induced pulmonary responses by the selective tryptase inhibitor 1,5-bis-{4-[(3-carbamimidoyl-benzenesulfonylamino)-methyl]-phenoxy}-pentane (AMG-126737)

Clifford D. Wright, Andrew M. Havill, Scot Middleton, Mohammed A. Kashem, David J. Dripps, William M. Abraham, David Thomson, Laurence E. Burgess

Biochemical Pharmacology · 1999 · 64 citations · 38 references

DOI

Concepts

References

38

Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation

John V. Fahy, Kwang Woo Kim, Homer A. Boushey · Journal of Allergy and Clinical Immunology · 1995 · 678 citations · Full text

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A sensitive new substrate for chymotrypsin

Eric G. Delmar, Corey Largman, James W. Brodrick et al. · Analytical Biochemistry · 1979 · 596 citations

, , +2

Mast cell tryptase is a mitogen for cultured fibroblasts.

Stephen J. Ruoss, Tobias Hartmann, George H. Caughey · Journal of Clinical Investigation · 1991 · 392 citations · Full text

, , +15

Activation of Pulmonary Mast Cells by Bronchoalveolar Allergen Challenge: <i>In Vivo</i> Release of Histamine and Tryptase in Atopic Subjects with and without Asthma

Sally E. Wenzel, Alpha A. Fowler, Lawrence B. Schwartz · American Review of Respiratory Disease · 1988 · 352 citations

, , +14

Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation.

Barry L. Gruber, Mary J. Marchese, Katsuya Suzuki et al. · Journal of Clinical Investigation · 1989 · 349 citations · Full text

, , +17