MAP1B Is Required for Netrin 1 Signaling in Neuronal Migration and Axonal Guidance

Abstract

These data indicate that MAP1B phosphorylation is controlled by Netrin 1 and that the lack of MAP1B impairs Netrin 1-mediated chemoattraction in vitro and in vivo. Thus, MAP1B may be a downstream effector in the Netrin 1-signaling pathway.