Role of nitric oxide formation in the regulation of haemodynamics and the release of noradrenaline and adrenaline

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Mechanobiology, Obligatory Role, Molecular Physiology +12

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.7K citations

Inflammation, Biological Activity, Endothelium-derived Relaxing Factor +8

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

Nitric Oxide, Oxidative Stress, Inflammation +21

Vascular endothelial cells synthesize nitric oxide from L-arginine

Richard Palmer, D. Ashton, Salvador Moncada · Nature · 1988 · 4.8K citations

Inflammation, Reactive Nitrogen Specie, Physiology +7

Localization of nitric oxide synthase indicating a neural role for nitric oxide

David S. Bredt, Paul M. Hwang, Solomon H. Snyder · Nature · 1990 · 3K citations

Neurophysiology, Neuroanatomy, Nitric Oxide +11