Concepedia

Cranial desmoid tumor associated with homozygous inactivation of the adenomatous polyposis coli gene in a 2‐year‐old girl with familial adenomatous polyposis

Deepthi C. de Silva, M Wright, David A. Stevenson, Caroline Clark, Elizabeth Gray, John D. Holmes, John Dean, Neva E. Haites, Malcolm G. Dunlop

Cancer · 1996 · 17 citations · 18 references

DOI

Abstract

These findings are compatible with the presence of a "second hit" inactivation of the APC gene and implicate this gene in the pathogenesis of desmoid tumors.

References

18

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

Masato Orita, Hiroyuki Iwahana, Hiroshi Kanazawa et al. · Proceedings of the National Academy of Sciences · 1989 · 3.6K citations · Full text

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Identification and characterization of the familial adenomatous polyposis coli gene

Joanna Groden, Andrew Thliveris, Wade S. Samowitz et al. · Cell · 1991 · 2.8K citations

, , +10

Identification of FAP Locus Genes from Chromosome 5q21

Kenneth W. Kinzler, Mef Nilbert, Li-Kuo Su et al. · Science · 1991 · 2.4K citations

, , +12

Localization of the gene for familial adenomatous polyposis on chromosome 5

Walter F. Bodmer, Clyde Bailey, J. G. Bodmer et al. · Nature · 1987 · 1.4K citations · Full text

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The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5

M. Leppert, M. Dobbs, Peter Scambler et al. · Science · 1987 · 676 citations

, , +19